Piza ē Vino is a pizzeria in Hartenbos, Mossel Bay, serving wood-fired pizzas with a sixty-hour fermented dough. The kitchen works from a recipe developed with an Italian chef, stretching the dough by hand and baking it in a wood-fired oven. The menu includes pasta dishes and family meals designed for four people.

The restaurant offers take-home pizza kits with dough, sauce, and mozzarella for two large pizzas. A loyalty programme gives regular guests access to special offers. The dining room is set up for groups, with tables that accommodate families and friends sharing meals.

The dough is the focus — fermented slowly to develop texture and flavor, then baked until the crust is crisp. Pasta sauces are cooked slowly, and ingredients are sourced with Italian tradition in mind. The restaurant opened in 2009 and has since expanded to multiple locations.